BDBM50102012 2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,2,3,4-tetrahydro-isoquinoline::CHEMBL520301::CHEMBL57567

SMILES COc1cccc2CN(CCCc3c[nH]c4ccc(F)cc34)CCc12

InChI Key InChIKey=HKMJCOCCPVLYPB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102012   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)
Affinity DataKi:  1.90nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)
Affinity DataKi:  6.46nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)
Affinity DataKi:  44.7nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed